Choo, HYP Choi, S Ryu, CK Kim, HJ Lee, IY Pae, AN Koh, HY 2024-01-21T08:45:32Z 2024-01-21T08:45:32Z 2021-09-03 2003-05-01 0968-0896 https://pubs.kist.re.kr/handle/201004/138583 The 3D-QSAR study of quinolinediones which showed potent inhibitory effect on the acetylcholine induced vaso-relaxation of rat aorta with the endothelium was conducted by CoMSIA. The statistical result, cross-validated q(2) (0.741) and r(2) (0.960) values, gave reliability to the prediction of inhibitory activity of this series. (C) 2003 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD NITRIC-OXIDE SYNTHASE POTENT INHIBITORS LY83583 QSAR study of quinolinediones with inhibitory activity of endothelium-dependent vasorelaxation by CoMSIA Article 10.1016/S0968-0896(03)00045-2 1 BIOORGANIC & MEDICINAL CHEMISTRY, v.11, no.9, pp.2019 - 2023 BIOORGANIC & MEDICINAL CHEMISTRY 11 9 2019 2023 scie scopus 000182101000009 2-s2.0-0037401606 Biochemistry & Molecular Biology Chemistry, Medicinal Chemistry, Organic Biochemistry & Molecular Biology Pharmacology & Pharmacy Chemistry Article NITRIC-OXIDE SYNTHASE POTENT INHIBITORS LY83583 QSAR quinolinedione CoMSIA