Yang, JY Shin, DC Park, S Chang, YS Kim, DH Ikonomou, MG 2024-01-21T11:12:28Z 2024-01-21T11:12:28Z 2021-09-05 2002-01 0045-6535 https://pubs.kist.re.kr/handle/201004/139878 We determined breast milk concentration of polychlorinated dibenzo-p-dioxins (PCDDs)/polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in 24 mothers living in Korea, and assessed the maternal body burden based on PCDDs/PCDFs and PCBs concentrations in breast milk and an infant intake rate through breast-feeding based on their concentration in breast milk. PCDDs/PCDFs and PCBs levels in breast milk from primipara mothers were found to be higher than those from multipara mothers. For total PCDDs/PCDFs TEQ level, 2,3,4,7,8-PeCDD was the predominant congener, and the proportion of 2,3,7,8-TCDD was less than 3% of total PCDDs/PCDFs TEQ level. For PCBs TEQ level, PCB-126 was the predominant congener. Maternal body burden levels of PCDDs/PCDFs and PCBs based on their concentrations in breast milk were 268-622 TEQ ng. The daily dioxin intakes of mothers were predicted to be 0.78. 2.18 TEQ pg/kg/day for PCDDs/PCDFs and 0.34-0.66 TEQ pg/kg/ day for PCBs. For the first year, the body burden of an infant was predicted to be 212 TEQ ng and the daily intake of an infant was predicted to be 85 TEQ pg/kg/day, assuming the mean dioxin-related compounds concentration (27.54 TEQ pg/g fat). (C) 2002 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD DIBENZO-P-DIOXINS POLYCHLORINATED-BIPHENYLS PCBS DICHLORODIPHENYL DICHLOROETHENE DDE THYROID-HORMONE STATUS FORMULA-FED INFANTS ORGANOCHLORINE PESTICIDES POSTNATAL EXPOSURE NEUROLOGICAL CONDITION CHLORINATED DIOXINS ADIPOSE-TISSUE PCDDs, PCDFs, and PCBs concentrations in breast milk from two areas in Korea: body burden of mothers and implications for feeding infants Article 10.1016/S0045-6535(01)00109-6 1 CHEMOSPHERE, v.46, no.3, pp.419 - 428 CHEMOSPHERE 46 3 419 428 scie scopus 000173519800006 2-s2.0-0036145363 Environmental Sciences Environmental Sciences & Ecology Article DIBENZO-P-DIOXINS POLYCHLORINATED-BIPHENYLS PCBS DICHLORODIPHENYL DICHLOROETHENE DDE THYROID-HORMONE STATUS FORMULA-FED INFANTS ORGANOCHLORINE PESTICIDES POSTNATAL EXPOSURE NEUROLOGICAL CONDITION CHLORINATED DIOXINS ADIPOSE-TISSUE PCDDs PCDFs PCBs breast milk maternal body burden infant feeding