Cha, JH Pae, AN Choi, KII Cho, YS Koh, HY Lee, E 2024-01-21T11:44:10Z 2024-01-21T11:44:10Z 2022-01-10 2001-09-07 1472-7781 https://pubs.kist.re.kr/handle/201004/140179 A new method has been developed for the synthesis of (E)-beta -methyl Baylis-Hillman adducts with high E-Z (>93%) selectivity in modest to good yields. The process consists of two steps: an indium-mediated allylation reaction and a simple base-catalyzed isomerization step. Various aldehydes were allylated with allyl bromides using indium under very mild conditions in aqueous media. The allylation reactions of aromatic and aliphatic aldehydes were largely accelerated by the presence of HCl. English ROYAL SOC CHEMISTRY An efficient approach to (E)-beta-methyl Baylis-Hillman adducts via indium-mediated allylation of aldehydes in aqueous media Article 1 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, no.17, pp.2079 - 2081 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 17 2079 2081 scie scopus 000171185700014 2-s2.0-0035823669 Chemistry, Organic Chemistry Article (E)- β -methyl baylis-hillman adducts