Shin, JA Cha, JH Pae, AN Choi, KI Koh, HY Kang, HY Cho, YS 2024-01-21T12:02:25Z 2024-01-21T12:02:25Z 2021-09-05 2001-08-06 0040-4039 https://pubs.kist.re.kr/handle/201004/140245 Indium-mediated allylation reactions of alpha-ketoimides derived from Oppolzer's sultam were accomplished in aqueous THF in good yields and excellent diastereomeric excesses. It could be a useful method for the preparation of enantiopure t-alpha -hydroxy acids. When the substituent of alpha-ketoimides was changed from phenyl to thiophenyl or furyl group, diastereoselectivity decreased in comparison to N-phenyl derivatives, but changing solvent to aqueous ethanol provided improved levels of diastereo selectivity. (C) 2001 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD ENANTIOSELECTIVE SYNTHESIS OXOCARBOXYLIC ACIDS Indium-mediated diastereoselective allylation reactions: preparation of tert-alpha-hydroxy acids Article 10.1016/S0040-4039(01)01064-4 1 TETRAHEDRON LETTERS, v.42, no.32, pp.5489 - 5492 TETRAHEDRON LETTERS 42 32 5489 5492 scie scopus 000170127200039 2-s2.0-0035817350 Chemistry, Organic Chemistry Article ENANTIOSELECTIVE SYNTHESIS OXOCARBOXYLIC ACIDS indium-mediated