Hahn, HG Nam, KD Mah, H 2024-01-21T12:06:43Z 2024-01-21T12:06:43Z 2021-09-05 2001-07-01 0385-5414 https://pubs.kist.re.kr/handle/201004/140321 A new methodology for the construction of 2-phenylimino-1,3-thiazolidin-4-one skeleton is described. Reaction of maleic anhydride (5a) or maleimides (5b, 5c) with thiourea (6) gave the corresponding 2-imino-1,3-thiazolidin-4-ones (7) and (9) respectively. The reaction proceeded with high yield in polar solvents. In non-polar solvents at high temperature, however, isothiocyanate (8) was formed as a by-product presumably by the pyrolysis of thiourea (6). The proposed mechanism of the reaction was discussed. English PERGAMON-ELSEVIER SCIENCE LTD A simple construction of 2-phenylimino-1,3-thiazolidin-4-ones Article 10.3987/COM-01-9227 1 HETEROCYCLES, v.55, no.7, pp.1283 - + HETEROCYCLES 55 7 1283 + scie scopus 000170864800008 2-s2.0-0035389544 Chemistry, Organic Chemistry Article Maleic Anhydride Maleimide Michael Addition Thiourea