Park, KD KWON, IL GREN Kim, Young Ha 2024-01-21T13:05:44Z 2024-01-21T13:05:44Z 2022-04-05 2000-12 0513-5796 https://pubs.kist.re.kr/handle/201004/140846 Tissue engineering can serve as an alternative treatment for a malfunctioning or lost organ. isolated and expanded cells adhere to a temporary scaffold, proliferate, and secrete their own extracellular matrices (ECM) replacing the biodegrading scaffold. The genitourinary system, composed of the kidney, ureter, bladder, urethra, and genital organs, is exposed to a variety of possible injury sires from the time of Fetal development. All the urinary organs are mainly composed of smooch muscle and uroepithelial cells and which may be approached by tissue engineering techniques. A large number of materials, including naturally-derived and synthetic polymers have been utilized to fabricate prostheses for the genitourinary system. Usually, whenever there is a lack of native urologic tissue, reconstruction is considered with native non-urologic tissue, such as, gastrointestinal segments, or skin or mucosa from multiple body sites. Engineering tissues using selective cell transplantation may provide a means to create functional new genitourinary tissues. This review concerns urinary tissues reconstructed with bladder uroepithelial cells and smooth muscle cells (SMCs) implanted on biodegradable polymer matrices. English 연세대학교의과대학 Tissue engineering of urinary organs Article 10.3349/ymj.2000.41.6.780 1 Yonsei Medical Journal, v.41, no.6, pp.780 - 788 Yonsei Medical Journal 41 6 780 788 N scopus 000166637700011 2-s2.0-0034566422 Medicine, General & Internal General & Internal Medicine Article BIODEGRADABLE POLYMER SCAFFOLDS ACELLULAR MATRIX GRAFT SMOOTH-MUSCLE TISSUE VESICOURETERAL REFLUX URETERAL REPLACEMENT STRUCTURES INVIVO BLADDER CHONDROCYTES REGENERATION RECONSTRUCTION ureter bladder urethra kidney tissue engineering scaffold