Shin, KH Lim, SS Jung, SH Ji, J Lee, EP Kim, Dong Chan Shin, Kye Jung Kim, Dong Jin PARK, SANG WOO 2024-01-21T14:16:20Z 2024-01-21T14:16:20Z 2022-04-05 2000-02 0253-6269 https://pubs.kist.re.kr/handle/201004/141581 Synthesis of pyridyloxy-, pyridyloxyphenoxy- and phenoxylphenoxyalkanate derivatives and their anti-inflammatory and analgesic activities were investigated. Analysis of structure-activity relationships showed that in pyridyloxyalkanoic acid derivatives anti-edematous potency was associated with the presence of chlorophenoxypropionic acid moiety and 2-nitrated methyl propionates contributed to the analgesic activity. English 대한약학회 Synthesis and anti-inflammatory and analgesic activities of pyridyloxy- and phenoxyalkanoic acid derivatives Article 10.1007/BF02976459 1 Archives of Pharmacal Research, v.23, no.1, pp.17 - 21 Archives of Pharmacal Research 23 1 17 21 N scopus 000085564000002 Chemistry, Medicinal Pharmacology & Pharmacy Pharmacology & Pharmacy Article antiinflammatory activity analgesic activity carrageenin-induced paw edema acetic acid writhing syndrome tail clip pressure test pyridyloxyalkanate pyridyloxyphenoxyalkanate phenoxylphenoxyalkanate