Choi, KI Cha, JH Cho, YS Pae, AN Jin, CB Yook, J Cheon, HG Jeong, DY Kong, JY Koh, HY 2024-01-21T15:02:17Z 2024-01-21T15:02:17Z 2021-09-04 1999-10-04 0960-894X https://pubs.kist.re.kr/handle/201004/141883 A series of 3-(3-phenylisoxazol-5-yl)methylidene-1-azabicycles synthesized showed different binding characteristics to acetylcholine receptors depending on the substituents on the phenyl ring. Small polar substituents gave preferential binding affinity to nicotinic receptors, and large hydrophobic substituents to muscarinic receptors. (C) 1999 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD MUSCARINIC RECEPTORS AGONISTS ANALOGS Binding affinities of 3-(3-phenylisoxazol-5-YL)methylidene-1-azabicycles to acetylcholine receptors Article 10.1016/S0960-894X(99)00477-1 1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.9, no.19, pp.2795 - 2800 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 9 19 2795 2800 scie scopus 000082960400004 2-s2.0-0033523641 Chemistry, Medicinal Chemistry, Organic Pharmacology & Pharmacy Chemistry Article MUSCARINIC RECEPTORS AGONISTS ANALOGS acetylcholine