Lee, SG Lee, SH Song, CE Chung, BY 2024-01-21T15:33:51Z 2024-01-21T15:33:51Z 2021-09-05 1999-05-07 0957-4166 https://pubs.kist.re.kr/handle/201004/142193 Novel C-2-symmetric chiral (4S,4'S)-bisphosphinobioxazine 2a, a six-membered analog of (4S,4S')bisphosphinobioxazoline (Phos-Biox, 1), and monophosphinobioxazine 2b have been synthesized and used as chiral ligands for Pd-catalyzed asymmetric allylic substitutions of rac-1,3-diphenyl-2-propenyl acetate with dimethyl malonate. C-2-Symmetric bisphosphinobioxazine 2a exhibited moderate enantioselectivities (63-84% ee) whereas excellent enantioselectivities (94-95% ee) were observed with monophosphinobioxazine 2b. (C) 1999 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD ASYMMETRIC HYDROSILYLATION ALKYLATIONS KETONES Novel phosphinobioxazines as chiral ligands in palladium-catalyzed enantioselective allylic substitution Article 10.1016/S0957-4166(99)00183-4 1 TETRAHEDRON-ASYMMETRY, v.10, no.9, pp.1795 - 1802 TETRAHEDRON-ASYMMETRY 10 9 1795 1802 scie scopus 000081079700022 2-s2.0-0345211514 Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry, Physical Chemistry Article ASYMMETRIC HYDROSILYLATION ALKYLATIONS KETONES phosphinobioxazine chiral ligand