Choi, MH Chung, BC Lee, W Lee, UC Kim, Y 2024-01-21T16:03:12Z 2024-01-21T16:03:12Z 2022-01-11 1999-01 0951-4198 https://pubs.kist.re.kr/handle/201004/142460 A gas chromatography/mass spectrometry (GC/MS) method is described which uses negative ion chemical ionization (NCI) and tandem mass spectrometry (MS/MS) for the determination of eight anabolic steroids in human urine. Eight anabolic steroids were derivatized by heptafluorobutyric anhydride (HFBA), and were determined using GC/NCI-MS and GC/NCI-MS/MS. The linear correlation coefficients for calibration in NCI-MS/MS were in the range 0.9880-0.9988, This method of derivatization with HFBA for use with GC/NCI was useful in determinations of 19-norandrosterone, boldenone, 19-noretiocholanolone, 2-methylandrosterone, nandrolone, 1-methyleneandrosterone, 1-methylandrosterone, 4-dihydroboldenone and mesterolone, The detection limits of this procedure were 5-20 ppb at a signal-to-noise (S/N) ratio of 3, Copyright (C) 1999 John Wiley & Sons, Ltd. English JOHN WILEY & SONS LTD INTERFERENCES CONFIRMATION SUBSTANCES URINE DRUGS Determination of anabolic steroids by gas chromatography negative-ion chemical ionization mass spectrometry and gas chromatography negative-ion chemical ionization tandem mass spectrometry with heptafluorobutyric anhydride derivatization Article 10.1002/(SICI)1097-0231(19990315)13:5<376::AID-RCM494>3.0.CO;2-# 1 RAPID COMMUNICATIONS IN MASS SPECTROMETRY, v.13, no.5, pp.376 - 380 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 13 5 376 380 scie scopus 000079189200013 2-s2.0-0000538798 Biochemical Research Methods Chemistry, Analytical Spectroscopy Biochemistry & Molecular Biology Chemistry Spectroscopy Article INTERFERENCES CONFIRMATION SUBSTANCES URINE DRUGS