Yu, JH 2024-01-21T17:06:05Z 2024-01-21T17:06:05Z 2022-01-11 1998-05-19 0960-894X https://pubs.kist.re.kr/handle/201004/143064 Sixty cell lines of monoclonal antibody were raised against a glucal hapten 1. Among them, Ab 405.4 showed alpha-mannosidase activity as k(cat) = 0.19 /day (k(cat)/k(uncat) = 110,000). The chemical modification study and pH profile study of this antibody indicated that carboxyl group(s) in the antigen binding site involved in catalytic mechanism. (C) 1998 Elsevier Science Ltd. All rights reserved. English PERGAMON-ELSEVIER SCIENCE LTD TRANSITION-STATE ANALOG GLYCOSIDASE BINDING alpha-mannosidase activity from antibody raised against a glucal antigen Article 10.1016/S0960-894X(98)00191-7 1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.8, no.10, pp.1145 - 1148 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8 10 1145 1148 scie scopus 000073738800004 2-s2.0-0032546501 Chemistry, Medicinal Chemistry, Organic Pharmacology & Pharmacy Chemistry Article TRANSITION-STATE ANALOG GLYCOSIDASE BINDING