Lee, JH Ju, YM Lee, WK Park, KD Kim, YH 2024-01-21T17:08:29Z 2024-01-21T17:08:29Z 2021-09-03 1998-05 0021-9304 https://pubs.kist.re.kr/handle/201004/143105 Polyethylene oxide (PEG) surfaces were prepared by the addition of PEG-and sulfonated PEO-containing amphiphilic block copolymers as surface-modifying additives in a segmented polyurethane (PU). PEO-PPO-PEO triblock copolymers (Pluronics) with different PEO chain lengths (from 2 to 80) were used as additives. The prepared film surfaces were characterized by the measurement of dynamic water contact angles and electron spectroscopy for chemical analysis. It was observed that the PU films containing 10 wt % of PEO additives were surface-saturated with the additives regardless of their PEO chain length, but the PEO chains were more projected from the film surfaces containing the additives with longer PEO chains. The water absorption of the films increased largely with the increasing PEO chain length of the additives. The addition of PEO additives produced film surfaces that were in a gel-like state. The films demonstrated some extraction of the PEO additives. However, the additives with higher molecular weights were entrapped more stably into the PU matrix. The mechanical properties (tensile strength and elongation) of the films were changed by the addition of PEO additives, but the differences were not significant compared to the control PU. The platelet adhesion on the film surfaces decreased with increasing PEO chain length of the additives. The film surface containing additives with long PEO chains (chain length of 80) was particularly effective in preventing platelet adhesion. The effect of negatively charged sulfonate groups on the prevention of platelet adhesion appeared only on the film surfaces containing additives with short PEO chains. For longer PEO chains, the chain mobility effect was more dominant than the negative charge effect on the prevention of platelet adhesion. (C) 1998 John Wiley & Sons, Inc. English JOHN WILEY & SONS INC POLY(ETHYLENE OXIDE)-GRAFTED POLYURETHANE PROTEIN ADSORPTION PROPERTIES BLOOD COMPATIBILITY POLYETHYLENE OXIDE AMPHIPHILIC POLYMERS PLASMA BEHAVIOR GLYCOL) FILMS ESCA Platelet adhesion onto segmented polyurethane surfaces modified by PEO- and sulfonated PEO-containing block copolymer additives Article 10.1002/(SICI)1097-4636(199805)40:2<314::AID-JBM17>3.0.CO;2-L 1 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, v.40, no.2, pp.314 - 323 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 40 2 314 323 scie scopus 000072677400017 2-s2.0-0032060392 Engineering, Biomedical Materials Science, Biomaterials Engineering Materials Science Article POLY(ETHYLENE OXIDE)-GRAFTED POLYURETHANE PROTEIN ADSORPTION PROPERTIES BLOOD COMPATIBILITY POLYETHYLENE OXIDE AMPHIPHILIC POLYMERS PLASMA BEHAVIOR GLYCOL) FILMS ESCA polyethylene oxide (PEG) sulfonated PEG surface modification segmented polyurethane platelet adhesion