Kim, HJ Woo, ER Shin, CG Park, H 2024-01-21T17:40:37Z 2024-01-21T17:40:37Z 2021-09-05 1998-01 0163-3864 https://pubs.kist.re.kr/handle/201004/143413 Bioassay-directed chromatographic fractionation of an ethyl acetate extract of the leaves of Acer okamotoanum using HIV-1 integrase afforded a new acylated flavonol glycoside, quercetin 3-0-(2 ",6 "-0-digalloyl)-beta-D-galactopyra (1), together with six known flavonol glycosides and three known phenolic compounds. The structure of the new compound was determined by spectroscopic methods. The most active compounds were quercetin 3-O-(2 "-galloyl)-alpha-L-arabinopyranoside (6) and 1, which exhibited IC50 values of 18.1 +/- 1.3 and 24.2 +/- 6.6 mu g/mL, respectively, against HIV-1 integrase. English AMER CHEMICAL SOC A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase Article 10.1021/np970171q 1 JOURNAL OF NATURAL PRODUCTS, v.61, no.1, pp.145 - 148 JOURNAL OF NATURAL PRODUCTS 61 1 145 148 N scie scopus 000071728100033 2-s2.0-0031911269 Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy Plant Sciences Pharmacology & Pharmacy Article TYPE-1 INTEGRASE C-13 NMR TANNINS POLYGALLOYLGLUCOSES HIV-1 integrase