Nam, KH Oh, CH Ham, YW Lee, KS Cho, JH 2024-01-21T18:08:17Z 2024-01-21T18:08:17Z 2022-01-11 1997-08 0365-6233 https://pubs.kist.re.kr/handle/201004/143655 The synthesis of a new series of 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octane-2,3-dione moiety is described. Their in vitro antibacterial activities against both Gram-positive and Gram-negative bateria are determined and the effect of substituent on the bicyclic ring as well as stereoisomerism was investigated. English VCH PUBLISHERS INC Synthesis and antibacterial activities of new 1 beta-methylcarbapenems having a 1,3-diazabicyclo[3.3.0]octan-2,4-dione moiety Article 10.1002/ardp.19973300808 1 ARCHIV DER PHARMAZIE, v.330, no.8, pp.268 - 270 ARCHIV DER PHARMAZIE 330 8 268 270 scie scopus A1997YC22900007 2-s2.0-0030768301 Chemistry, Medicinal Chemistry, Multidisciplinary Pharmacology & Pharmacy Pharmacology & Pharmacy Chemistry Article carbapenem antibacterial activity substituent effect stereoisomerism