Kim, DC Kim, DJ Shin, KJ Park, SW Yoo, KH 2024-01-21T18:33:30Z 2024-01-21T18:33:30Z 2022-01-10 1997-04-01 0385-5414 https://pubs.kist.re.kr/handle/201004/143850 3-Phenyl-5,6-dihydroimidazo[2,1-b]thiazole (1) as a nucleophile reacted with acetylenic acid esters such as ethyl propiolate and dimethyl acetylenedicarboxylate to give the new ring transformation compounds (2-oxo-imidazoline-1-yl)acrylic acid ethyl esters (6a-b) and [2-oxo-imidazoline-1-yl]but-2-enedioic acid diethylesters (7a-b), respectively. Similarly, treatment of reactive imidazo[2,1-b]thiazolium betaines (3a-b) with acetylenic acid derivatives led to the corresponding ring transformation compounds. This reaction proceeded by the participation of water, and the resulting compounds were obtained in a mixture of cis and trans isomers. English PERGAMON-ELSEVIER SCIENCE LTD New ring transformation reaction of imidazothiazole with acetylenic acid esters Article 1 HETEROCYCLES, v.45, no.4, pp.773 - 778 HETEROCYCLES 45 4 773 778 scie scopus A1997XG65200015 2-s2.0-18844398142 Chemistry, Organic Chemistry Article imidazothiazole