Suh, JW Lee, SH Chung, BC Park, J 2024-01-21T18:40:59Z 2024-01-21T18:40:59Z 2022-01-11 1997-01-24 0378-4347 https://pubs.kist.re.kr/handle/201004/143979 With a newly modified analytical method, the concentrations of free and acetylated urinary polyamines simultaneously determined in a control group (32 cases) and patients with various types of cancers (104 cases, 20 males and 84 females) by gas chromatography -nitrogen-phosphorus detection. Significant concentration differences between normal subjects and various cancer patients were found. The various types of cancers (advanced gastric carcinoma, ovarian cancer, acute myelocyte leukemia, non-Hodgkin's lymphoma) gave unique patterns of urinary polyamine profile as well as significant differences of concentration. To indirectly evaluate the possible involvement of enzymes, precursor-to-product concentration ratios were compared between controls and patients with various types of cancers. English ELSEVIER SCIENCE BV Urinary polyamine evaluation for effective diagnosis of various cancers Article 10.1016/S0378-4347(96)00266-6 1 JOURNAL OF CHROMATOGRAPHY B, v.688, no.2, pp.179 - 186 JOURNAL OF CHROMATOGRAPHY B 688 2 179 186 scie scopus A1997WV31200002 2-s2.0-0031050560 Biochemical Research Methods Chemistry, Analytical Biochemistry & Molecular Biology Chemistry Article polyamines putrescine spermidine spermine N-acetylputrescine