Cao, Y Woo, K Yeung, LK Carpenter, GB Sweigart, DA 2024-01-21T18:41:03Z 2024-01-21T18:41:03Z 2021-09-01 1997-01-21 0276-7333 https://pubs.kist.re.kr/handle/201004/143980 Nucleophilic addition of MeMgCl and PhMgBr to the A-ring aromatic steroid complex [(eta 6-3,17-dimethoxyestradiol)Mn(CO)(3)](+) gives stable eta(5)-cyclohexadienyl complexes and occurs at the C-1 site meta to the -OMe group when the metal is on the ''beta'' side of the steroid; addition to the ''alpha'' analogue is less regioselective due to steric interactions and occurs at C-1, C-2, and C-4. A manganese-mediated procedure is reported for the functionalization of estrone at the C-1 position to give 1-methylestrone in 42% yield. English AMER CHEMICAL SOC ORGANOMANGANESE ARENE COMPLEXES X-RAY STRUCTURE MANGANESE TRICARBONYL ELECTROPHILIC REACTIVITY ESTRADIOL DERIVATIVES CARBONYL-COMPLEXES BETA-ESTRADIOL = C5ME5 A-RING RECEPTOR Nucleophilic addition reactions and functionalization of (3-methoxyestrone)- and (3,17-dimethoxyestradiol)manganese tricarbonyl complexes Article 10.1021/om960820d 1 ORGANOMETALLICS, v.16, no.2, pp.178 - 183 ORGANOMETALLICS 16 2 178 183 scie scopus A1997WD81200006 Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry Article ORGANOMANGANESE ARENE COMPLEXES X-RAY STRUCTURE MANGANESE TRICARBONYL ELECTROPHILIC REACTIVITY ESTRADIOL DERIVATIVES CARBONYL-COMPLEXES BETA-ESTRADIOL = C5ME5 A-RING RECEPTOR nucleophilic addition manganese tricarbonyl crystal structure aromatic steroid