Kim, KM Jun, MJ Sohn, YS 2024-01-21T19:04:08Z 2024-01-21T19:04:08Z 2022-01-10 1997-01 0277-5387 https://pubs.kist.re.kr/handle/201004/144142 A H-1 NMR study has-been carried out on (diamine)platinum(II) complexes of 1,3-dithian-2- ylidenemalonate (DTAYM) and 1,3-dithiepane-2-ylidenemalonate (DTEYM) ligands as anionic leaving group in aqueous solution. Only the O,S-chelated isomer was observed in solution for all the DTAYM complexes regardless of the kind of carrier ligand amine as was in the solid state. However, both O,S-and S,S'-chelated isomers were observed in solution for DTEYM complexes, which show linkage isomerism from the O,S-chelate to the thermodynamically more stable S,S'-chelate. The rate of linkage isomerism of the DTEYM complexes was found to be dependent on their amine co-ligands. Molecular dynamics of the DTAYM complexes was also discussed based on their temperature-dependent NMR spectra. The crystal structure of the S,S'-isomer of (NH3),Pt(DTEYM). H2O was determined whereas that of the O,S-isomer could not be obtained due to its poor crystallinity. (C) 1997 Elsevier Science Ltd. English PERGAMON-ELSEVIER SCIENCE LTD NUCLEAR MAGNETIC-RESONANCE CIS-DIAMMINEDIAQUAPLATINUM(II) CATION PLATINUM COMPLEXES ANTITUMOR-ACTIVITY RING REVERSAL AMINO-ACIDS GLUTATHIONE CISPLATIN METHIONINE REACTIVITY Linkage isomerism of (diamine)platinum(II) complexes of sulfur-containing ylidenemalonate ligands Article 1 POLYHEDRON, v.16, no.21, pp.3705 - 3711 POLYHEDRON 16 21 3705 3711 scie scopus A1997XR70900002 2-s2.0-0037807782 Chemistry, Inorganic & Nuclear Crystallography Chemistry Crystallography Article NUCLEAR MAGNETIC-RESONANCE CIS-DIAMMINEDIAQUAPLATINUM(II) CATION PLATINUM COMPLEXES ANTITUMOR-ACTIVITY RING REVERSAL AMINO-ACIDS GLUTATHIONE CISPLATIN METHIONINE REACTIVITY (diamine)platinum(II) 1,3-dithian-2-ylidenemalonate 1,3-dithiepane-2-ylidenemalonate O,S-chelate S,S&apos -chelate linkage isomerism