Ko, SB Lee, YS Lee, JY Ham, WH Park, HK 2024-01-21T19:13:14Z 2024-01-21T19:13:14Z 2021-09-04 1996-10 0253-6269 https://pubs.kist.re.kr/handle/201004/144296 A series of aminothiazolylcephalosporin derivatives (1a similar to 1c) having pyridinylethenyl group at C-3 position was prepared starting from phosphonium salt 3 and 2-, 3- or 4-pyridinecarboxaldehyde and the antibacterial activity of these compounds was investigated. Among them, 4-pyridinylethenyl derivative was more active than 2- and 3-pyridinylethenyl derivatives against Staphylococcus aureus and Escherichia coli. English PHARMACEUTICAL SOCIETY KOREA Synthesis and biological activity of C-3 pyridinylethene-substituted cephalosporins Article 10.1007/BF02976388 1 ARCHIVES OF PHARMACAL RESEARCH, v.19, no.5, pp.411 - 415 ARCHIVES OF PHARMACAL RESEARCH 19 5 411 415 N scie scopus A1996VP91500014 2-s2.0-20544464466 Chemistry, Medicinal Pharmacology & Pharmacy Pharmacology & Pharmacy Article ESTERS cephalosporins antibacterial activity pyridinylethenyl Wittig reaction pyridinecarboxaldehyde