KIM, IJ YOO, KH SHIN, KJ KIM, DJ PARK, SW 2024-01-21T21:13:30Z 2024-01-21T21:13:30Z 2022-01-10 1995-01 0039-7911 https://pubs.kist.re.kr/handle/201004/145406 New stereoisomeric N-bridged heterocycles, 4-oxo-1,3-diazabicyclo[3.3.0]octanes(4) were synthesized from trans-4-hydroxy-L-proline(1). Thiohydantoins 3 as the key intermediates were prepared by nucleophilic addition of 1 to isothiocyanates, and subsequent cyclization. These thiohydantoins 3 were readily desulfurized to provide 4. English MARCEL DEKKER INC AN EFFICIENT CONSTRUCTION OF 4-OXO-1,3-DIAZABICYCLO[3.3.0]OCTANES VIA THIOHYDANTOINS Article 10.1080/00397919508011476 1 SYNTHETIC COMMUNICATIONS, v.25, no.24, pp.4001 - 4010 SYNTHETIC COMMUNICATIONS 25 24 4001 4010 scie scopus A1995TK12700008 2-s2.0-0029586643 Chemistry, Organic Chemistry Article 4-Oxo-1 3-diazabicyclo[3.3.0]octane