SUH, YH LEE, IS KIM, SS CHOI, W PARK, CW CHUNG, MH LIM, JK 2024-01-21T22:35:49Z 2024-01-21T22:35:49Z 2022-01-10 1993-03 1532-0456 https://pubs.kist.re.kr/handle/201004/146098 1. The values of both K(d) and B(max) of [H-3] dihydroalprenolol binding in the cerebral cortical membranes of old-aged (12 month old) SAM-P/l were not significantly different compared with those of young (2 month old) SAM-P/l. 2. The values of K(i) of metoprolol in the young and old aged SAM were 119 +/- 39.5 nM and 157 +/- 55 nM, respectively. 3. The values of beta1/beta2 ratio of the young and old aged SAM were 1.67 +/- 0.15 and 1.64 +/- 0.13, respectively. 4. These results suggest that there were no significant changes of binding characteristics of beta1 and beta2 adrenoceptors during aging in the cerebral cortex of SAM. English ELSEVIER SCIENCE INC LIGAND-BINDING CHARACTERISTICS OF [H-3] DIHYDROALPRENOLOL IN CEREBRAL CORTICAL MEMBRANES OF YOUNG AND OLD SENESCENCE-ACCELERATED MOUSE Article 1 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v.104, no.3, pp.423 - 426 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 104 3 423 426 scie A1993LG47100012 Biochemistry & Molecular Biology Endocrinology & Metabolism Toxicology Zoology Biochemistry & Molecular Biology Endocrinology & Metabolism Toxicology Zoology Article brain [3H] dihydroalprenolol binding BETA-2-ADRENERGIC RECEPTORS RAT CORTEX SUBTYPES BETA-2-ADRENERGIC RECEPTORS