PARK, H LEE, YS SHIM, SC 2024-01-21T22:36:10Z 2024-01-21T22:36:10Z 2021-09-02 1993-02 0253-2964 https://pubs.kist.re.kr/handle/201004/146104 https://scienceon.kisti.re.kr/srch/selectPORSrchArticle.do?cn=JAKO199313464459004 A synthetic route to (+)-isocarbacyclin starting from (-)-tricyclo[3.3.0.0(2,8)]octan-3-one 6 is described. The key intermediate 4 has been synthesized from 6 by a sequential introduction of methoxycarbonyl group at C-12 and the oxygen functionality at C-9alpha (PG numbering) for the construction of alpha- and omega-side chain, and then converted to isocarbacyclin methyl ester 2. English KOREAN CHEMICAL SOC A NEW CHIRAL SYNTHETIC ROUTE TO (+)-ISOCARBACYCLIN Article 1 BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.14, no.1, pp.86 - 91 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 14 1 86 91 N scie A1993KT40500025 Chemistry, Multidisciplinary Chemistry Article BUILDING-BLOCKS (+)-9(0)-METHANO-DELTA-6(9-ALPHA)-PGI1 PROSTACYCLIN