Lim, S. Kim, D. Kim, D.J. Kim, Y.K. 2024-02-21T05:03:12Z 2024-02-21T05:03:12Z 2017 1064-3745 https://pubs.kist.re.kr/handle/201004/148753 Abnormal tau aggregation is a pathological hallmark of neurodegenerative disease classified as tauopathy. Preventing tau aggregation becomes an important therapeutic strategy to cure tau-mediated neurodegeneration. Here, we describe a method to investigate intracellular tau aggregation by using a recently developed tau aggregation cell-based model named tau-BiFC. High-throughput and high-contents screening method for quantifying intracellular tau aggregation would expedite the discovery of drugs that inhibit tau aggregation. ？ Springer Science+Business Media New York 2017. 2 Humana Press Inc. Image-based analysis of intracellular Tau aggregation by using Tau-BiFC cell model Book 10.1007/978-1-4939-6598-4_22 341 347