Yhee, Ji Young Koo, Heebeom Lee, Dong Eun Choi, Kuiwon Kwon, Ick Chan Kim, Kwangmeyung 2024-02-21T05:03:35Z 2024-02-21T05:03:35Z 2011 0065-3195 https://pubs.kist.re.kr/handle/201004/148762 Chitosan and its derivatives have been widely used for various biomedical applications because of their unique chemical and biological characters. The amine groups in the backbone of chitosan allow chemical modification to change the physical properties of chitosan. Based on hydrophobic or charge interactions with this chitosan polymer backbone, stable self-assembled nanoparticles can be fabricated in aqueous condition. These nanosized structures enable intravenous injection and show large accumulation in tumor tissue, indicating great potential in imaging and drug delivery. The main objective of this review is to introduce various chitosan nanoparticles and their recent applications for tumor diagnosis and therapy. 2 SPRINGER-VERLAG BERLIN Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy Book 10.1007/12_2011_119 139 161