Shin, Donghwa Kim, Soomin Lee, Duck-Hyung Han, Seo-Jung 2024-06-13T02:00:17Z 2024-06-13T02:00:17Z 2024-06-13 2024-06 0022-3263 https://pubs.kist.re.kr/handle/201004/150059 Mild, metal-free, and operationally simple three-component coupling reactions involving arynes, phosphites, and acrylates have been achieved. The reaction proceeded well with alpha- or beta-substituted acrylates. Additionally, various functional groups were tolerated under these reaction conditions, resulting in diverse ortho-3-propanoate-substituted aryl phosphonates. Moreover, the reaction can be used to synthesize a range of organophosphorus compounds present in natural products, materials, and biologically active compounds. English American Chemical Society Synthetic Strategies toward Ortho-3-propanoate Substituted Aryl Phosphonates by Three-Component Coupling Reactions of Arynes, Phosphites, and Acrylates Article 10.1021/acs.joc.4c00672 1 The Journal of Organic Chemistry, v.89, no.11, pp.8035 - 8040 The Journal of Organic Chemistry 89 11 8035 8040 N scie scopus 001234402900001 2-s2.0-85194484457 Chemistry, Organic Chemistry Article DESIGN INHIBITOR ALKENES P-ARYLATION