Choi Pilju Kim, Ji yool Han Yong Seong Kim, Jeong-Kook Jeon, Young Sic Kim, Young Joo Kim, Taejung Ham, Jung yeob 2024-01-12T02:30:25Z 2024-01-12T02:30:25Z 2023-09-25 2023-04 https://pubs.kist.re.kr/handle/201004/75739 https://ijans.org/index.php/ijans/article/view/731 This research aimed to design, optimize, and compare batch and flow-type microwave-assisted processing using temperature, time, and microwave effects to accelerate the decarboxylation of cannabidiolic acid (CBDA) to cannabidiol (CBD) in hemp extract. The conversion yield of decarboxylation was investigated at different heating temperatures and processing times, and the resulting yields were compared with those obtained using two other methods. The optimum conversion yields of the batch and flow-type microwave-assisted processing of decarboxylation were 90.3% (120 °C for 30 min) and 92.8% (90 °C for 30 min) in hemp extract, respectively. As a result, batch and flow-type microwave-assisted processing are effective and viable methods for the decarboxylation of CBDA to CBD at relatively short residence times and high throughput. English ANATOLIA ACAD SCIENCES EFFECTS OF BATCH AND CONTINUOUS-FLOW MICROWAVE-ASSISTED PROCESS FOR THE DECARBOXYLATION OF CANNABIDIOLIC ACID IN HEMP EXTRACT Article 10.5281/zenodo.8372625 1 International Journal of Agricultural and Natural Sciences, v.16, no.1, pp.74 - 80 International Journal of Agricultural and Natural Sciences 16 1 74 80 N other Cannabis sativa L. cannabidiol acid cannabidiol decarboxylation microwave