이성준 Park, Kyuha 금정은 An, Soojung Yu, Ki Jun Kim, Hyungmin Shin, Mikyung Son, Donghee 2024-01-12T02:33:37Z 2024-01-12T02:33:37Z 2022-12-29 2023-01 https://pubs.kist.re.kr/handle/201004/75862 An electrocorticogram (ECoG) is the electrical activity obtainable from the cerebral cortex and an informative source with considerable potential for future advanced applications in various brain-interfacing technologies. Considerable effort has been devoted to developing biocompatible, conformal, soft, and conductive interfacial materials for bridging devices and brain tissue; however, the implementation of brain-adaptive materials with optimized electrical and mechanical characteristics remains challenging. Herein, we present surface electrode arrays using the soft tough ionic conductive hydrogel (STICH). The newly proposed STICH features brain-adaptive softness with Young’s modulus of ~9.46 kPa, which is sufficient to form a conformal interface with the cortex. Additionally, the STICH has high toughness of ~36.85 kJ/mm3, highlighting its robustness for maintaining the solid structure during interfacing with wet brain tissue. The stretchable metal electrodes with a wavy pattern printed on the elastomer were coated with the STICH as an interfacial layer, resulting in an improvement of the impedance from 60 kΩ to 10 kΩ at 1 kHz after coating. Acute in vivo experiments for ECoG monitoring were performed in anesthetized rodents, thereby successfully realizing conformal interfacing to the animal’s cortex and the sensitive recording of electrical activity using the STICH-coated electrodes, which exhibited a higher visual-evoked potential (VEP) amplitude than that of the control device. English MDPI Open Access Publishing Stretchable Surface Electrode Arrays Using an Alginate/PEDOT:PSS-Based Conductive Hydrogel for Conformal Brain Interfacing Article 10.3390/polym15010084 1 Polymers, v.15, no.1, pp.84 Polymers 15 1 84 Y scie scopus 000910241800001 Polymer Science Polymer Science Article SILICON PROBES OPTOGENETICS TECHNOLOGY CIRCUITS SYSTEMS stretchable electronics soft electronics implantable electronics brain interface electrocorticogram conductive hydrogel