Ji, Su Hyun Kim Soomin NAM, GHIL SOO Lee, Duck-Hyung Han, Seojung 2024-01-12T02:35:38Z 2024-01-12T02:35:38Z 2022-11-08 2022-11 1523-7060 https://pubs.kist.re.kr/handle/201004/75948 An efficient and straightforward method for the synthesis of aryl(alkynyl)phosphinates was developed via a three-component coupling reaction involving arynes, phosphites, and alkynes. An array of aryl(alkynyl)phosphinates were produced from both aryl and aliphatic group-substituted acetylenes. This opera-tionally simple reaction is tolerant to many functional groups, affording various aryl(alkynyl)phosphinates in moderate to good yields. The synthetic utility of alkynyl phosphinates afforded by this method was demonstrated by the elaboration of the products into various phosphorus-containing compounds. English American Chemical Society Synthetic Strategy for Aryl(alkynyl)phosphinates by a Three-Component Coupling Reaction Involving Arynes, Phosphites, and Alkynes Article 10.1021/acs.orglett.2c03231 1 Organic Letters, v.24, no.45, pp.8295 - 8299 Organic Letters 24 45 8295 8299 N scie scopus 000883958700001 Chemistry, Organic Chemistry Article P-ARYLATION ALKYNYLPHOSPHONATES BIOSYNTHESIS PHOSPHONATES ACTIVATION