Deshmukh, Pratiksha P. Malankar, Gauri S. Sakunthala, Arunima Navalkar, Ambuja Maji, Samir K. Dhiraj, P. Murale Saravanan, Raju Manjare, Sudesh T. 2024-01-12T03:32:46Z 2024-01-12T03:32:46Z 2022-02-22 2022-02 1477-9226 https://pubs.kist.re.kr/handle/201004/76807 Mercury ions are toxic and exhibit hazardous effects on the environment and biological systems, and thus demand for the selective and sensitive detection of mercury has become considerably an important issue. Here, we have developed a diselenide containing coumarin-based probe 3 for the selective detection of Hg(ii) with a "turn-on" response (a 48 fold increase in fluorescence intensity) at 438 nm. The probe could quantitatively detect Hg(ii) with a detection limit of 1.32 mu M in PBS solution. Moreover, the probe has operable efficiency over the physiological range with an increase in the quantum yield from 1.2% to 57.3%. The reaction of the probe with Hg(ii) yielded a novel monoselenide based coumarin 4via diselenide oxidation, which was confirmed by single crystal XRD. Furthermore, the biological use of the probe for the detection of Hg(ii) was confirmed in the MCF-7 cell line. To the best of our knowledge, this is the first reaction-based probe for Hg(ii) via diselenide oxidation. English Royal Society of Chemistry An efficient chemodosimeter for the detection of Hg(ii) via diselenide oxidation Article 10.1039/d1dt04038c 1 Dalton Transactions, v.51, no.6, pp.2269 - 2277 Dalton Transactions 51 6 2269 2277 N scie scopus 000746125400001 2-s2.0-85124436989 Chemistry, Inorganic & Nuclear Chemistry Article MERR FAMILY PROTEINS FLUORESCENT CHEMOSENSOR COLORIMETRIC SENSORS SIMPLE COUMARINS RAPID DETECTION MERCURY PROBE IONS HG2+ SELENIUM