KIM TAEJUNG Kyu Hyuk Jeong Buyng Su Hwang Youngseok Kim Masaya Nakata Ham, Jungyeob 2024-01-12T06:12:13Z 2024-01-12T06:12:13Z 2021-09-29 2018-03-18 0065-7727 https://pubs.kist.re.kr/handle/201004/79437 In this study, a novel and simple method for the preparation of various arylnaphthalene lactone natural products was developed and used to synthesize diphyllin (10), justicidin A (12), cilinaphthalide B (13), taiwanin E (15), chinensinaphthol (16), taiwanin E methyl ether (17), chinensinaphthol methyl ether (18), justicidin C (21) and justicidin D (22). The syntheses proceeded via Hauser-Kraus annulation of cyanophthalides (7a and 7b) and Suzuki-Miyaura crosscoupling of arylnaphthalene lactones having a sulfonate group (9, 14, 19, and 20) with the corresponding potassium aryltrifluoroborates. English AMER CHEMICAL SOC Natural Products Arylnaphthalene Lactone Justicidin Total Synthesis of Arylnaphthalene Lactone Natural Products via Hauser-Kraus Annulation and Suzuki-Miyaura Cross-Coupling Reaction Conference 1 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water US New Orleans 2018-03-18 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 000435539905219