Park, Kijun Kim, Seunghoi Jo, Yejin Park, Jae InWoo Kim Hwang, Sooyoung Lee, Yeontaek Kim, So Yeon Seo, Jungmok 2024-01-12T06:35:29Z 2024-01-12T06:35:29Z 2022-08-24 2023-07 2452-199X https://pubs.kist.re.kr/handle/201004/79896 Implantable biomedical devices require an anti-biofouling, mechanically robust, low friction surface for a prolonged lifespan and improved performance. However, there exist no methods that could provide uniform and effective coatings for medical devices with complex shapes and materials to prevent immune-related side effects and thrombosis when they encounter biological tissues. Here, we report a lubricant skin (L-skin), a coating method based on the application of thin layers of bio-adhesive and lubricant-swellable perfluoropolymer that impart anti-biofouling, frictionless, robust, and heat-mediated self-healing properties. We demonstrate biocompatible, mechanically robust, and sterilization-safe L-skin in applications of bioprinting, microfluidics, catheter, and long and narrow medical tubing. We envision that diverse applications of L-skin improve device longevity, as well as anti-biofouling attributes in biomedical devices with complex shapes and material compositions. ？ 2022 The Authors English Elsevier Lubricant skin on diverse biomaterials with complex shapes via polydopamine-mediated surface functionalization for biomedical applications Article 10.1016/j.bioactmat.2022.07.019 1 Bioactive Materials, v.25, pp.555 - 568 Bioactive Materials 25 555 568 Y scie scopus 000973264200001 2-s2.0-85135529632 Engineering, Biomedical Materials Science, Biomaterials Engineering Materials Science Article COATINGS DEVICES FLOW Lubricant-infused Anti-biofouling Biointerface Biomaterials Biomedical applications