Kim, C. Kang, E. Kim, Y.E. Lee, K.J. Kim, T.S. Kang, J.Y. 2024-01-12T07:24:06Z 2024-01-12T07:24:06Z 2022-03-07 2009-06 0000-0000 https://pubs.kist.re.kr/handle/201004/80953 In this paper, we propose a microfluidic chip to generate well-defined microcapsule. In order to make core-shell microcapsule, a simple design capable of 3-dimensional hydrodynamic focusing was embedded in the proposed microfluidic chip. Cell suspension is focused 3-dimensional hydrodynamic in microchannel by the hillock based geometries, and then the core-shell structure of alginate microcapsules with thin membrane can be clearly identified. The mouse embryonic carcinoma cell line, P19, was cultured in the capsules and spherical EB (more than 70 %) with strong compaction was successfully formed within 2 days. ？2009 IEEE. English IEEE Novel microfluidic chip generating mono-disperse core-shell microcapsules Conference 10.1109/SENSOR.2009.5285660 1 TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems, pp.2022 - 2025 TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems 2022 2025 US Denver, CO 2009-06-21 TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems 2-s2.0-71449084075