KIM WAN JOO Kim, Jae Duck VERIANSYAH BAMBANG Kim, Jaehoon 오성근 Raymond R Tjandrqwinata 2024-01-12T07:52:31Z 2024-01-12T07:52:31Z 2021-09-29 2007-10-26 https://pubs.kist.re.kr/handle/201004/81415 Effects of solvent types and extraction methods (conventional liquid stirring extraction, soxhlet extraction, supercritical carbon dioxide extraction) were investigated for effective extraction of bioactive Asiaticoside from centella asiatica. Various organic and aqueous solvent were screened by stirring and soxhlet method. Compare to water and ethanol, the extraction with methanol is more effective in the extraction of asiaticoside from centella asiatica with about 8.19mg /g by conventional liquid stirring extraction. However, methanol is toxic and not concern as GRAS(Generally Regarded as safe : FDA) solvent. The sohxlet extraction showed that asiaticoside extraction reached a maximum value 11.78 mg/g at 65 % (v/v) ethanol in water. This result indicates that asiaticoside is soluble in polar solvents namely aqueous ethanol and asiaticoside is hydrophilic or water-soluble. The solvent extraction by Soxhlet is the best method for asiaticoside extraction. SCCO2 extraction (supercritical carbon dioxide) with the addition of ethanol-water cosolvent is superior in terms of low liquid solvent consumption. English 한국화학공학회 supercritical carbon dioxide extraction centella asiatica Asiaticoside conventional liquid stirring extraction shoxhlet extraction SCCO2 extraction Extraction of Asiaticoside from centella asiatica: Effects of solvents and extraction methods Conference 2 2007년 한국화학공학회 가을 총회 및 학술대회, pp.1564 2007년 한국화학공학회 가을 총회 및 학술대회 1564 1564 KO 한국과학기술원 2007-10-26 Theories and Applications of Chem. Eng., 2007, Vol. 13, No. 2