Tailoring MgxMn1-xFe2O4 Superparamagnetic Nanoferrites for Magnetic Fluid Hyperthermia Applications

Abstract

A superparamagnetic nanoferrite (SPNF) with high magnetic moment, AC magnetically induced heating (AC-heating) capacity, and good biocompatibility is the most vital part of magnetic fluid hyperthermia for utilizing it in the clinics. Herein, we precisely tune magnetic properties and AC-heating characteristics of MgxMn(1-x)Fe(2)O(4) SPNF via chemically controlling the cations' concentration and distribution to develop a tailored MgxMn1-xFe2O4 SPNF as a potential magnetic fluid hyperthermia agent. The magnetic and AC-heating characteristics of the tailored MgxMn1-xFe2O4 SPNF are strongly dependent on the Mg/Mn cations' concentration and distribution, and Mg(0.285)Mn0.715Fe(2)O(4) SPNF exhibits the highest saturation magnetization and AC-heating capacity as well as high biocompatibility.