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Site-selective labeling at Cys302 of aldehyde dehydrogenase unveils a selective mitochondrial stain

Authors
Kim, Yun Kyung; Lee, Jin Kak; Lee, Jun-Seok; Yoon, Chang No; Chang, Young-Tae
Issue Date
2011-06
Publisher
ROYAL SOC CHEMISTRY
Citation
MOLECULAR BIOSYSTEMS, v.7, no.8, pp.2375 - 2378
Abstract
A mitochondria-trackable fluorophore, CDy2, selectively labels Cys302 in the active site of mitochondrial aldehyde dehydrogenase (ALDH2).
Keywords
LIVING CELLS; IN-VIVO; RHODAMINE-123; DISULFIRAM; INHIBITION; PROBE; LIVING CELLS; IN-VIVO; RHODAMINE-123; DISULFIRAM; INHIBITION; PROBE; imaging probe; fluorescence; target identification; binding site
ISSN
1742-206X
URI
https://pubs.kist.re.kr/handle/201004/130309
DOI
10.1039/c1mb05137g
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KIST Article > 2011
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