Preparation of folic acid-chitosan complex (eco-yellow) and its application for adsorption of mutagens and carcinogens

Authors
Jeon, H.-K.Kim, Y.-J.Ryu, J.-C.
Issue Date
2009-03
Citation
Toxicology and Environmental Health Sciences, v.1, no.1, pp.64 - 68
Abstract
Folic acid, a pteridine derivative, is abundant in liver and green plants and is a growth factor for some bacteria. Chitosan is a unique polysaccharide derived from chitin and is utilized as adsorbents of organic trace pollutants in environmental water sample. In this study, we have found that chitosan was suitable as a solid support to carry folic acid. And it was examined that folic acid could form an insoluble material when mixed with chitosan, a polyglucosamine, and the solid chitosan-folic acid complex (eco-yellow) thus prepared could efficiently trap polycyclic mutagenic compounds. The adsorption of the test compounds was observed using UV/Visible spectrometry. The order of extent of removal by eco-yellow was B[a]P (62. 0%)>2-AA (56. 2%)>QC (55. 9%)>Trp-p-2 (40. 2%). From these results, eco-yellow may be expected as a useful adsorber for several polycyclic mutagens and carcinogens. ? 2009 The Korean Society of Environmental Risk Assessment and Health Science and Springer.
Keywords
Adsorption; Carcinogens; Folic acid-chitosan complex; Polycyclic mutagens
ISSN
2005-9752
URI
https://pubs.kist.re.kr/handle/201004/132721
DOI
10.1007/BF03216465
Appears in Collections:
KIST Article > 2009
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