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dc.contributor.authorCha, JH-
dc.contributor.authorPae, AN-
dc.contributor.authorChoi, KI-
dc.contributor.authorCho, YS-
dc.contributor.authorKim, WH-
dc.contributor.authorHan, YS-
dc.contributor.authorYun, HC-
dc.contributor.authorLee, JS-
dc.contributor.authorKoh, HY-
dc.contributor.authorLee, L-
dc.date.accessioned2024-01-21T10:04:50Z-
dc.date.available2024-01-21T10:04:50Z-
dc.date.created2021-09-01-
dc.date.issued2002-10-
dc.identifier.issn0141-5492-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/139197-
dc.description.abstractAn NADPH-dependent carbonyl reductase that shows (3R)-selective reducing activity for alpha-substituted-beta-ketoesters was purified from Kluyveromyces marxianus and racemic alkyl 2-substituted-3-oxobutanoates were reduced to the corresponding (2S,3R)- or (2R,3R)-2-substituted-3-hydroxybutanoates with enantiomeric purity (>99%) and diastereoselectivity (24 similar to 98%).-
dc.languageEnglish-
dc.publisherKLUWER ACADEMIC PUBL-
dc.subjectBAKERS-YEAST-
dc.subjectTRANSFORMATIONS-
dc.titleStereochemical control in diastereoselective reduction of alpha-substituted-beta-ketoesters using a reductase purified from Kluyveromyces marxianus-
dc.typeArticle-
dc.identifier.doi10.1023/A:1020649316546-
dc.description.journalClass1-
dc.identifier.bibliographicCitationBIOTECHNOLOGY LETTERS, v.24, no.20, pp.1695 - 1698-
dc.citation.titleBIOTECHNOLOGY LETTERS-
dc.citation.volume24-
dc.citation.number20-
dc.citation.startPage1695-
dc.citation.endPage1698-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000178645400009-
dc.identifier.scopusid2-s2.0-0036805544-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.type.docTypeArticle-
dc.subject.keywordPlusBAKERS-YEAST-
dc.subject.keywordPlusTRANSFORMATIONS-
dc.subject.keywordAuthorasymmetric reduction-
dc.subject.keywordAuthorbiocatalyst-
dc.subject.keywordAuthorcarbonyl reductase-
dc.subject.keywordAuthordiastereoselectivity-
dc.subject.keywordAuthorKluyveromyces marxianus-
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