DSpace at KISTKIST Article2001

Full metadata record

DC Field Value Language
dc.contributor.authorKim, YH-
dc.contributor.authorCheong, CS-
dc.contributor.authorLee, SH-
dc.contributor.authorKim, KS-
dc.date.accessioned2024-01-21T12:05:47Z-
dc.date.available2024-01-21T12:05:47Z-
dc.date.created2021-09-04-
dc.date.issued2001-07-30-
dc.identifier.issn0957-4166-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/140304-
dc.description.abstractKetorolac was resolved into each enantiomer by interesterification using lipase B from Candida antarctica. The acid reacted with various alcohols and the ester and acid were resolved up to > 99% e.e. when reacted with octanol, which was the best result. To increase reactivity and enantioselectivity, the experimental conditions were adjusted by varying temperature, solvent, alcohols and reaction time. (C) 2001 Published by Elsevier Science Ltd.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectMETABOLIC CHIRAL INVERSION-
dc.subject2-ARYLPROPIONIC ACIDS-
dc.subjectLIPASE-
dc.subjectENANTIOSELECTIVITY-
dc.subjectESTERIFICATION-
dc.subjectCONSEQUENCES-
dc.titleEnzymatic kinetic resolution of ketorolac-
dc.typeArticle-
dc.identifier.doi10.1016/S0957-4166(01)00332-9-
dc.description.journalClass1-
dc.identifier.bibliographicCitationTETRAHEDRON-ASYMMETRY, v.12, no.13, pp.1865 - 1869-
dc.citation.titleTETRAHEDRON-ASYMMETRY-
dc.citation.volume12-
dc.citation.number13-
dc.citation.startPage1865-
dc.citation.endPage1869-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.identifier.wosid000171278300008-
dc.identifier.scopusid2-s2.0-0035973757-
dc.relation.journalWebOfScienceCategoryChemistry, Inorganic & Nuclear-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalResearchAreaChemistry-
dc.type.docTypeArticle-
dc.subject.keywordPlusMETABOLIC CHIRAL INVERSION-
dc.subject.keywordPlus2-ARYLPROPIONIC ACIDS-
dc.subject.keywordPlusLIPASE-
dc.subject.keywordPlusENANTIOSELECTIVITY-
dc.subject.keywordPlusESTERIFICATION-
dc.subject.keywordPlusCONSEQUENCES-
dc.subject.keywordAuthorkinetic resolution-
Appears in Collections:
KIST Article > 2001
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML
Show Simple Item Record

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE