The development of a nucleus staining fluorescent probe for dynamic mitosis imaging in live cells

Title
The development of a nucleus staining fluorescent probe for dynamic mitosis imaging in live cells
Authors
Krishna Kanta Ghosh정연미강남영이정렬Wan Si Yan Diana김준영유재덕김도희김윤경장영태
Keywords
DNA; fluorescence; Cell imaging; probe
Issue Date
2015-04
Publisher
Chemical communications
Citation
VOL 51, 9336-9338
Abstract
A low-toxicity nucleus staining fluorescent probe, CDb12, was developed for real time mitosis imaging in live cells. CDb12 was identified by unbiased high-throughput imaging-based screening of a new xanthone library (AX). Unlike the conventional Hoechst dye, the low toxicity of CDb12 allows long term monitoring of cell division over more than one cell cycle.
URI
https://pubs.kist.re.kr/handle/201004/49936
ISSN
13597345
Appears in Collections:
KIST Publication > Article
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