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dc.contributor.author함정엽-
dc.contributor.author강기성-
dc.contributor.author이혜정-
dc.contributor.author이다혜-
dc.date.accessioned2021-06-09T04:17:20Z-
dc.date.available2021-06-09T04:17:20Z-
dc.date.issued2016-12-
dc.identifier.citationVOL 37-2018-
dc.identifier.issn0253-2964-
dc.identifier.other47982-
dc.identifier.urihttps://pubs.kist.re.kr/handle/201004/65199-
dc.description.abstractCyaniding 3-O-glucoside is a flavonoid compound isolated from the fruits of the Lonicera caerulea. In the present study, we investigated the effects of L. caerulea extract and its active component cyaniding 3-O-glucoside on insulin release in INS-1 cells. L. caerulea extract and cyanidin 3-O-glucoside activated the secretion of insulin that lead to diminished glucose production in INS-1 cells. Cyanidin 3-O-glucoside also enhanced the phosphorylation of insulin receptor, insulin receptor substrate 1, and phosphoinositide 3-kinase protein expressions in INS-1 cells. These results suggest that cyanidin 3-O-glucoside is an active component of L. caerulea that enhances insulin production and activates insulin signaling.-
dc.publisherBulletin of the Korean Chemical Society-
dc.subjectCyanidin 3-O-glucoside-
dc.subjectGlucose response-
dc.subjectInsulin secretion-
dc.subjectLonicera caerulea-
dc.titleCyanidin 3-O-glucoside Isolated from Lonicera caerulea Fruit Improves Glucose Response in INS-1 Cells by Improving Insulin Secretion and Signaling-
dc.typeArticle-
dc.relation.page20152018-
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