Challenges in wide implementation of genome editing for crop improvement
- Challenges in wide implementation of genome editing for crop improvement
- 정제형; 서용원
- Genome editing; homologous recombination (HR); sequence specific nucleases (SSNs); crop improvement
- Issue Date
- Journal of Crop Science and Biotechnology
- VOL 20, NO 2-135
- Genome editing technologies using customizable sequence specific nucleases (SSNs) enables precise genome modification in plants, which has revolutionized functional genomics research as well as crop improvement. Applicability of SSN-mediated genome editing ranges from targeted gene knockout and single base modification to multiple gene stacking into desired genomic sites. However, there are still considerable challenges in implementing genome editing technologies for practical crop improvement. Here, we briefly discuss the technological challenges, especially those associated with the delivery of SSNs and with homologous recombination-mediated genome editing, and address some promising solutions to overcome the issues.
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- KIST Publication > ETC
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