Highly selective fluorescence turn-on probe for glutathione
- Title
- Highly selective fluorescence turn-on probe for glutathione
- Authors
- 이상희; 임수연; 박승범; 김해조
- Keywords
- Fluorescence; GSH; Hydrogen bond; Michael addition
- Issue Date
- 2011-07
- Publisher
- Tetrahedron letters
- Citation
- VOL 52, NO 30-3904
- Abstract
- An activated coumarin-3-phenyl enone (1) by an intramolecular hydrogen bond has shown a selective and ratiometric response toward GSH and Cys over other natural amino acids through the Michael addition reaction of a thiol group to 1. When GSH was added to 1, a prominent color change together with a fluorescence turn-on property was observed so that submillimolar GSH was detectable.
- URI
- https://pubs.kist.re.kr/handle/201004/67298
- ISSN
- 0040-4039
- Appears in Collections:
- KIST Publication > Article
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