Size-controlled synthesis of polymerized DNA nanoparticles for targeted anticancer drug delivery
- Size-controlled synthesis of polymerized DNA nanoparticles for targeted anticancer drug delivery
- 최기영; 남건욱; 김태형; 김영민; 양경직; 채덕영; Lawrence B. Mensah; 노영훈
- Issue Date
- Chemical communications
- VOL 55, NO 34-4908
- We synthesized size-tunable polymerized DNA nanoparticles (PDNs) for cancer-targeted drug delivery via sequential processes of rolling circle amplification, condensation, and layer-by-layer assembly. The PDNs selectively delivered anti-sense oligonucleotides to target cancer cells and exhibited size-dependent gene regulation efficacy.
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