Development of Highly Sensitive Glucose Sensor Based on Clustered Superparamagnetic Iron Oxide Nanoparticles
- Development of Highly Sensitive Glucose Sensor Based on Clustered Superparamagnetic Iron Oxide Nanoparticles
- 한성민; 최원석; 기재홍
- SPIONs; Glucose sensor; Nanoparticle; Clustering
- Issue Date
- 대한의용생체공학회 추계학술대회
Superparamagnetic iron oxide nanoparticles (SPIONs) are used in a wide range of fields, such as contrast agents in magnetic resonance imaging and targeted drug delivery using the natural property that can move to a specific site in a magnetic field. It is also known to act as an artificial peroxidase that has a stable catalytic effect even a wide pH and temperature when compared with the natural peroxidase expressed in the body. Here, we have demonstrated a highly sensitive glucose sensor based on clustered SPIONs that coated with PLGA (Poly(lactic-co-glycolic acid)) via hydrophobic effect. We show that the clustered SPIONs have a higher sensitivity to glucose than the previous paper that has discussed with just a single iron oxide core.
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