Regulation of Deubiquitinating Enzymes by Post-Translational Modifications

Title
Regulation of Deubiquitinating Enzymes by Post-Translational Modifications
Authors
김은경신상철타누자다스송은주
Issue Date
2020-06
Publisher
International journal of molecular sciences
Citation
VOL 21, NO 11, 4028
Abstract
Ubiquitination and deubiquitination play a critical role in all aspects of cellular processes, and the enzymes involved are tightly regulated by multiple factors including posttranslational modifications like most other proteins. Dysfunction or misregulation of these enzymes could have dramatic physiological consequences, sometimes leading to diseases. Therefore, it is important to have a clear understanding of these regulatory processes. Here, we have reviewed the posttranslational modifications of deubiquitinating enzymes and their consequences on the catalytic activity, stability, abundance, localization, and interaction with the partner proteins.
URI
https://pubs.kist.re.kr/handle/201004/71669
ISSN
1422-0067
Appears in Collections:
KIST Publication > ETC
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