Showing results 15 to 27 of 27
Issue Date | Title | Author(s) |
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2019-11 | Optimization study towards more potent thiazolidine-2,4-dione IKK-beta modulator: Synthesis, biological evaluation and in silico docking simulation | Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Yang, Jeong-Eun; Elsherbeny, Mohamed H.; Paik, Sora; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo |
2022-12 | Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
2018-09-05 | Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of A beta-induced mPTP opening for Alzheimer's disease | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo |
2018-05-10 | Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents | Kang, Seokmin; Lee, Jung Moo; Jeon, Borami; Elkamhawy, Ahmed; Paik, Sora; Hong, Jinpyo; Oh, Soo-Jin; Paek, Sun Ha; Lee, C. Justin; Hassan, Ahmed H. E.; Kang, Sang Soo; Roh, Eun Joo |
2020-01-01 | Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds | Farag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo |
2023-05 | Synthesis and Biological Evaluation of O-6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases | Hassan, Ahmed H. E.; Kim, Hyeon Jeong; Park, Keontae; Choi, Yeonwoo; Moon, Suyeon; Lee, Chae Hyeon; Kim, Yeon Ju; Cho, Soo Bin; Gee, Min Sung; Lee, Danbi; Park, Jong-Hyun; Lee, Jong Kil; Ryu, Jong Hoon; Park, Ki Duk; Lee, Yong Sup |
2024-08 | Synthesis and biological evaluation of O4′-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents | Hassan, Ahmed H. E.; Choi, Yeonwoo; Kim, Rium; Kim, Hyeon Jeong; Almatary, Aya M.; El-Sayed, Selwan M.; Lee, Yeongae; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup |
2016-01-01 | Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists | Hoang Nam Vu; Kim, Ji Young; Hassan, Ahmed H. E.; Choi, Kihang; Park, Jong-Hyun; Park, Ki Duk; Lee, Jae Kyun; Pae, Ae Nim; Choo, Hyunah; Min, Sun-Joon; Cho, Yong Seo |
2018-01-20 | Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of A beta-induced mitochondrial dysfunction in Alzheimer's disease | Elkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Roh, Eun Joo |
2017-12-01 | Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-beta-induced toxicity | Park, Jung-eun; Elkamhawy, Ahmed; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo |
2018-10-01 | Synthesis of oxidative metabolites of CRA13 and their analogs: Identification of CRA13 active metabolites and analogs thereof with selective CB2R affinity | Hassan, Ahmed H. E.; Cho, Min Chang; Kim, Hye In; Yang, Ji Seul; Park, Kyung Tae; Hwang, Ji Young; Jang, Choon-Gon; Park, Ki Duk; Lee, Yong Sup |
2015-06-05 | Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4+3] Cycloaddition/SmI2-Pinacol Coupling | Hassan, Ahmed H. E.; Lee, Jae Kyun; Pae, Ae Nim; Min, Sun-Joon; Cho, Yong Seo |
2020-02-15 | Thiazolidine-2,4-dione-based irreversible allosteric IKK-beta kinase inhibitors: Optimization into in vivo active anti-inflammatory agents | Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Paik, Sora; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo |