Browsing byAuthorRoh, Eun Joo

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Showing results 44 to 66 of 66

Issue DateTitleAuthor(s)
2018-05-10Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agentsKang, Seokmin; Lee, Jung Moo; Jeon, Borami; Elkamhawy, Ahmed; Paik, Sora; Hong, Jinpyo; Oh, Soo-Jin; Paek, Sun Ha; Lee, C. Justin; Hassan, Ahmed H. E.; Kang, Sang Soo; Roh, Eun Joo
2020-01-01Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compoundsFarag, Ahmed K.; Hassan, Ahmed H. E.; Ahn, Byung Sun; Park, Ki Duk; Roh, Eun Joo
2021-09Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico ScreeningElkamhawy, Ahmed; Ammar, Usama M.; Paik, Sora; Abdellattif, Magda H.; Elsherbeny, Mohamed H.; Lee, Kyeong; Roh, Eun Joo
2012-08-15Small molecules that protect against beta-amyloid-induced cytotoxicity by inhibiting aggregation of beta-amyloidLee, Yun Suk; Kim, Hye Yun; Kim, YoungSoo; Seo, Jae Hong; Roh, Eun Joo; Han, Hogyu; Shin, Kye Jung
2013-02-06Stereoselective synthesis of (-)-8-epi-swainsonine starting with a chiral aziridineLee, Baeck Kyoung; Choi, Hwan Geun; Roh, Eun Joo; Lee, Won Koo; Sim, Taebo
2008-10-15Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1)Roh, Eun Joo; Keller, Jason M.; Olah, Zoltan; Iadarola, Michael J.; Jacobson, Kenneth A.
2014-08-01Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitorsPark, Byung Sun; Al-Sanea, Mohammad M.; Abdelazem, Ahmed Z.; Park, Hye Mi; Roh, Eun Joo; Park, Hyun-Mee; Yoo, Kyung Ho; Sim, Taebo; Tae, Jin Sung; Lee, So Ha
2020-07Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insightsAl-Sanea, Mohammad M.; Elkamhawy, Ahmed; Paik, Sora; Lee, Kyeong; El Kerdawy, Ahmed M.; Abbas, Bukhari Syed Nasir; Roh, Eun Joo; Eldehna, Wagdy M.; Elshemy, Heba A. H.; Bakr, Rania B.; Farahat, Ibrahim Ali; Alzarea, Abdulaziz, I; Alzarea, Sami, I; Alharbi, Khalid S.; Abdelgawad, Mohamed A.
2013-03-15Synthesis and biological evaluation of 1-(2-hydroxy-3-phenyloxypropyl)piperazine derivatives as T-type calcium channel blockersPark, Jung-eun; Ji, Wan Keun; Jang, Jae Wan; Pae, Ae Nim; Choi, Keehyun; Choi, Ki Hang; Kang, Jahyo; Roh, Eun Joo
2015-11Synthesis and Biological Evaluation of 2-Phenylimino-5((5-phenylfuran-2-yl)methylene)thiazolidin-4-ones as IKK2 InhibitorsKim, Hee Sook; Shin, Min Jae; Lee, Byungho; Oh, Kwang-Seok; Choo, Hyunah; Pae, Ae Nim; Roh, Eun Joo; Nam, Ghilsoo
2011-10-01Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockersWoo, Hyun Min; Lee, Yun Suk; Roh, Eun Joo; Seo, Seon Hee; Song, Chi Man; Chung, Hye Jin; Pae, Ae Nim; Shin, Kye Jung
2013-10-15Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitorsPark, Jung-eun; Song, Chiman; Choi, Keehyun; Sim, Taebo; Moon, Bongjin; Roh, Eun Joo
2019-01-01Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitorsAl-Sanea, Mohammad M.; Elkamhawy, Ahmed; Paik, Sora; Bua, Silvia; Lee, So Ha; Abdelgawad, Mohamed A.; Roh, Eun Joo; Eldehna, Wagdy M.; Supuran, Claudiu T.
2018-01-20Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of A beta-induced mitochondrial dysfunction in Alzheimer's diseaseElkamhawy, Ahmed; Park, Jung-eun; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Park, Beoung-Geon; Roh, Eun Joo
2008-08-01Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockersLee, Hyung Kook; Lee, Yun Suk; Roh, Eun Joo; Rhim, Hyewhon; Lee, Jae Yeol; Shin, Kye Jung
2017-12-01Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-beta-induced toxicityPark, Jung-eun; Elkamhawy, Ahmed; Hassan, Ahmed H. E.; Pae, Ae Nim; Lee, Jiyoun; Paik, Sora; Park, Beoung-Geon; Roh, Eun Joo
2012-12-15Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's diseaseLee, Yun Suk; Kim, Hee; Kim, Young-Ho; Roh, Eun Joo; Han, Hogyu; Shin, Kye Jung
2016-10Synthesis of novel arylaminoquinazolinylurea derivatives and their antiproliferative activities against bladder cancer cell lineKim, Jung Hun; Kwak, Yeonui; Song, Chiman; Roh, Eun Joo; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Choi, Jung Hoon; Yoo, Kyung Ho
2015-08Synthesis of quinolinylaminopyrimidines and quinazolinylmethylaminopyrimidines with antiproliferative activity against melanoma cell lineLee, Jun A.; Roh, Eun Joo; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Jong Seung; Yoo, Kyung Ho
2015-11-15Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular dockingElkamhawy, Ahmed; Farag, Ahmed Karam; Viswanath, Ambily Nath Indu; Bedair, Tarek M.; Leem, Dong Gyu; Lee, Kyung-Tae; Pae, Ae Nim; Roh, Eun Joo
2020-02-15Thiazolidine-2,4-dione-based irreversible allosteric IKK-beta kinase inhibitors: Optimization into in vivo active anti-inflammatory agentsElkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Paik, Sora; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo
2022-05Trifluoperazine and Its Analog Suppressed the Tumorigenicity of Non-Small Cell Lung Cancer Cell; Applicability of Antipsychotic Drugs to Lung Cancer TreatmentJeong, Joo Yeon; Park, Haangik; Yoo, Hong; Kim, Eun-Jin; Jeon, Borami; Lee, Jong Deog; Kang, Dawon; Lee, Changjoon Justin; Paek, Sun Ha; Roh, Eun Joo; Yi, Gwan-Su; Kang, Sang Soo
2017-01Trifluoperazine, a Well-Known Antipsychotic, Inhibits Glioblastoma Invasion by Binding to Calmodulin and Disinhibiting Calcium Release Channel IP3RKang, Seokmin; Hong, Jinpyo; Lee, Jung Moo; Moon, Hyo Eun; Jeon, Borami; Choi, Jungil; Yoon, Nal Ae; Paek, Sun Ha; Roh, Eun Joo; Lee, C. Justin; Kang, Sang Soo

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