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Showing results 1 to 12 of 12

Issue DateTitleAuthor(s)
2020-06-01Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting (V600E)BRAFAbdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Ammar, Usama M.; Mersal, Karim I.; Yoo, Kyung Ho; Oh, Chang-Hyun
2021-02-01Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38 alpha/MAPK14 inhibitorAli, Eslam M. H.; Abdel-Maksoud, Mohammed S.; Hassan, Rasha Mohamed; Mersal, Karim I.; Ammar, Usama M.; Se-In, Choi; He-Soo, Han; Kim, Hee-Kwon; Lee, Anna; Lee, Kyung-Tae; Oh, Chang-Hyun
2019-12Design, synthesis, and anticancer activity of imidazo[2,1-b]oxazole-based RAF kinase inhibitorsAbdel-Maksoud, Mohammed S.; Ammar, Usama M.; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Mersal, Karim I.; Ali, Eslam M. H.; Yoo, Kyung Ho; Lee, Kyung-Tae; Oh, Chang-Hyun
2021-01Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAF(V600E) inhibitorsAli, Eslam M. H.; Abdel-Maksoud, Mohammed S.; Ammar, Usama M.; Mersal, Karim, I; Yoo, Kyung Ho; Jooryeong, Park; Oh, Chang-Hyun
2021-04-05Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAF(V600E)/p38 alpha inhibitorsAli, Eslam M. H.; El-Telbany, Rania Farag A.; Abdel-Maksoud, Mohammed S.; Ammar, Usama M.; Mersal, Karim, I; Zaraei, Seyed-Omar; El-Gamal, Mohammed, I; Choi, Se-In; Lee, Kyung-Tae; Kim, Hee-Kwon; Lee, Kwan Hyi; Oh, Chang-Hyun
2021-10Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide derivatives in LPS-induced RAW264.7 macrophage cellsMersal, Karim I.; Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Ammar, Usama M.; Zaraei, Seyed-Omar; Kim, Jae-Min; Kim, Su-Yeon; Lee, Kyung-Tae; Lee, Kwan Hyi; Kim, Si-Won; Park, Hyun-Mee; Ji, Mi-Jung; Oh, Chang-Hyun
2021-05Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma ActivityAbdel-Maksoud, Mohammed S.; El-Gamal, Mohammed, I; Lee, Bong S.; El-Din, Mahmoud M. Gamal; Jeon, Hong R.; Kwon, Dow; Ammar, Usama M.; Mersal, Karim, I; Ali, Eslam M. H.; Lee, Kyung-Tae; Yoo, Kyung Ho; Han, Dong Keun; Lee, Jae Kyun; Kim, Garam; Choi, Hong Seok; Kwon, Young Jik; Lee, Kwan Hyi; Oh, Chang Hyun
2023-12Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cellsMersal, Karim I.; Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Ammar, Usama M.; Zaraei, Seyed-Omar; Haque, Md Mamunul; Das, Tanuza; Hassan, Noha F.; Kim, Eunice EunKyeong; Lee, Jun-Seok; Park, Hajeung; Lee, Kwan Hyi; El-Gamal, Mohammed I.; Kim, Hee-Kwon; Ibrahim, Tamer M.; Oh, Chang-Hyun
2022-09Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological StudiesElkamhawy, Ahmed; Paik, Sora; Ali, Eslam M. H.; Hassan, Ahmed H. E.; Kang, So Jin; Lee, Kyeong; Roh, Eun Joo
2020-10-15Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular dockingAmmar, Usama M.; Abdel-Maksoud, Mohammed S.; Mersal, Karim, I; Ali, Eslam M. H.; Yoo, Kyung Ho; Choi, Hong Seok; Lee, Jae Kyun; Cha, Sun Young; Oh, Chang-Hyun
2020-07Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screeningAmmar, Usama M.; Abdel-Maksoud, Mohammed S.; Ali, Eslam M. H.; Mersal, Karim, I; Yoo, Kyung Ho; Oh, Chang-Hyun
2019-04-01Thieno[2,3-d] pyrimidine as a promising scaffold in medicinal chemistry: Recent advancesAli, Eslam M. H.; Abdel-Maksoud, Mohammed S.; Oh, Chang-Hyun
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