2019-12 | All-trans Retinoic Acid Overcomes Acquired Resistance to PLX4032 via Inhibition of PIN1 in Melanoma Cells | Kim, Garam; Bhattarai, Poshan Yugal; Oh, Chang-Hyun; Choi, Hong Seok |
2013-09 | Antiproliferative Diarylpyrazole Derivatives as Dual Inhibitors of the ERK Pathway and COX-2 | El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun |
2016-12 | Design and synthesis of a new series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives possessing antiproliferative activity against melanoma cells | Khan, Mohammad Ashrafuddin; El-Gamal, Mohammed I.; Tarazi, Hamadeh; Choi, Hong Seok; Oh, Chang-Hyun |
2019-03-31 | Design and synthesis of a novel series of highly potent RAF kinase-inhibiting triarylpyrazole derivatives with potential antiproliferative activity against melanoma | El-Gamal, Mohammed; Khan, Mohammad Ashrafuddin; Oh, Chang-Hyun; Choi, Hong Seok; Tarazi, Hamadeh |
2011-11 | Design, Synthesis, and Antiproliferative Activity of 3,4-Diarylpyrazole-1-carboxamide Derivatives Against Melanoma Cell Line | El-Gamal, Mohammed I.; Choi, Hong Seok; Cho, Hae-Guk; Hong, Jun Hee; Yoo, Kyung Ho; Oh, Chang-Hyun |
2012-09-20 | Design, Synthesis, and Preliminary Cytotoxicity Evaluation of New Diarylureas and Diarylamides Possessing 1,3,4-Triarylpyrazole Scaffold | Choi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Hong, Jun Hee; Baek, Daejin; Choi, Kihang; Oh, Chang-Hyun |
2015-05-05 | Design, synthesis, in vitro antiproliferative evaluation, and kinase inhibitory effects of a new series of imidazo[2,1-b]thiazole derivatives | Abdel-Maksoud, Mohammed S.; Kim, Mi-Ryeong; El-Gamal, Mohammed I.; El-Din, Mahmoud M. Gamal; Tae, Jinsung; Choi, Hong Seok; Lee, Kyung-Tae; Yoo, Kyung Ho; Oh, Chang-Hyun |
2021-05 | Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity | Abdel-Maksoud, Mohammed S.; El-Gamal, Mohammed, I; Lee, Bong S.; El-Din, Mahmoud M. Gamal; Jeon, Hong R.; Kwon, Dow; Ammar, Usama M.; Mersal, Karim, I; Ali, Eslam M. H.; Lee, Kyung-Tae; Yoo, Kyung Ho; Han, Dong Keun; Lee, Jae Kyun; Kim, Garam; Choi, Hong Seok; Kwon, Young Jik; Lee, Kwan Hyi; Oh, Chang Hyun |
2013-09 | Inhibitory Effects of a New 1H-Pyrrolo[3,2-c]pyridine Derivative, KIST101029, on Activator Protein-1 Activity and Neoplastic Cell Transformation Induced by Insulin-Like Growth Factor-1 | Yun, Hyo Jeong; Kim, Garam; Khanal, Prem; Kim, Karam; Oh, Chang-Hyun; Choi, Hoo-Kyun; Sohn, Honglae; Choi, Hong Seok |
2020-10-15 | Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking | Ammar, Usama M.; Abdel-Maksoud, Mohammed S.; Mersal, Karim, I; Ali, Eslam M. H.; Yoo, Kyung Ho; Choi, Hong Seok; Lee, Jae Kyun; Cha, Sun Young; Oh, Chang-Hyun |
2013-12 | New diarylamides and diarylureas possessing 8-amino(acetamido) quinoline scaffold: Synthesis, antiproliferative activities against melanoma cell lines, kinase inhibition, and in silico studies | Koh, Eun Jeong; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Hong, Jun Hee; Lee, Sang-gi; Yoo, Kyung Ho |
2011-12 | New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studies | Choi, Won-Kyoung; El-Gamal, Mohammed I.; Choi, Hong Seok; Baek, Daejin; Oh, Chang-Hyun |
2020-09 | Novel Imidazo[2,1-b]oxazole Derivatives Inhibit Epithelial Cell Transformation and Triple Negative Breast Cancer Tumorigenesis | Bhattarai, Poshan Yugal; Oh, Chang-Hyun; Kim, Garam; Kim, Min Soo; Lee, Bong Sang; Choi, Hong Seok |
2013-07 | Novel Quinolinylaminoisoquinoline Bioisosteres of Sorafenib as Selective RAFI Kinase Inhibitors: Design, Synthesis, and Antiproliferative Activity against Melanoma Cell Line | Cho, Hye Jung; El-Gamal, Mohammed Ibrahim; Oh, Chang-Hyun; Lee, So Ha; Sim, Taebo; Kim, Garam; Choi, Hong Seok; Choi, Jung Hoon; Yoo, Kyung Ho |
2022-06 | Potent Imidazothiazole-based Inhibitor of BRAF V600E Overcomes Acquired Resistance via Inhibition of RAF Dimerization in PLX4032-resistant Melanoma | Poudel, Muna; Kim, Garam; Bhattarai, Poshan Yugal; Shin, Seung; Zaraei, Seyed-Omar; Oh, Chang-Hyun; Choi, Hong Seok |
2012-11-20 | Synthesis and Antiproliferative Activity of New Aminoisoquinolinylurea Derivatives against Melanoma Cell Line | Cho, Hye Jung; El-Gamal, Mohammed I.; Oh, Chang-Hyun; Lee, So Ha; Kim, Garam; Hong, Jun Hee; Choi, Hong Seok; Yoo, Kyung Ho |