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Showing results 1 to 18 of 18

Issue Date	Title	Author(s)
2010-08-12	A Type-II Kinase Inhibitor Capable of Inhibiting the T315I "Gatekeeper" Mutant of Bcr-Abl	Choi, Hwan Geun; Ren, Pingda; Adrian, Francisco; Sun, Fangxian; Lee, Hyun Soo; Wang, Xia; Ding, Qiang; Zhang, Guobao; Xie, Yongping; Zhang, Jianming; Liu, Yi; Tuntland, Tove; Warmuth, Markus; Manley, Paul W.; Mestan, Juergen; Gray, Nathanael S.; Sim, Taebo
2010-09-22	An efficient and enantioselective total synthesis of naturally occurring L-783277	Choi, Hwan Geun; Son, Jung Beom; Park, Dong-Sik; Ham, Young Jin; Hah, Jung-Mi; Sim, Taebo
2013-10-23	An efficient synthesis of 1,4-dideoxy-1,4-imino-D- and L-arabinitol and 1,4-dideoxy-1,4-imino-D- and L-xylitol from chiral aziridines	Choi, Hwan Geun; Park, Dong-Sik; Lee, Won Koo; Sim, Taebo
2018-11-12	Brain injury induces HIF-1 alpha-dependent transcriptional activation of LRRK2 that exacerbates brain damage	Bae, Yun-Hee; Joo, Hyejin; Bae, Jinhyun; Hyeon, Seung Jae; Her, Song; Ko, Eunhwa; Choi, Hwan Geun; Ryu, Hoon; Hur, Eun-Mi; Bu, Youngmin; Lee, Byoung Dae
2017-01	Covalent Guanosine Mimetic Inhibitors of G12C KRAS	Xiong, Yuan; Lu, Jia; Hunter, John; Li, Lianbo; Scott, David; Choi, Hwan Geun; Lim, Sang Min; Manandhar, Anuj; Gondi, Sudershan; Sim, Taebo; Westover, Kenneth D.; Gray, Nathanael S.
2012-08-15	Development of 'DFG-out' inhibitors of gatekeeper mutant kinases	Choi, Hwan Geun; Zhang, Jianming; Weisberg, Ellen; Griffin, James D.; Sim, Taebo; Gray, Nathanael S.
2016-08	Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo	Sundberg, Thomas B.; Liang, Yanke; Wu, Huixian; Choi, Hwan Geun; Kim, Nam Doo; Sim, Taebo; Johannessen, Liv; Petrone, Adam; Khor, Bernard; Graham, Daniel B.; Latorre, Isabel J.; Phillips, Andrew J.; Schreiber, Stuart L.; Perez, Jose; Shamji, Alykhan F.; Gray, Nathanael S.; Xavier, Ramnik J.
2015-12-10	Discovery of Inhibitors That Overcome the G1202R Anaplastic Lymphoma Kinase Resistance Mutation	Hatcher, John M.; Bahcall, Magda; Choi, Hwan Geun; Gao, Yang; Sim, Taebo; George, Rani; Jaenne, Pasi A.; Gray, Nathanael S.
2015-01-08	Discovery of Type II Inhibitors of TGF beta-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)	Tan, Li; Nomanbhoy, Tyzoon; Gurbani, Deepak; Patricelli, Matthew; Hunter, John; Geng, Jiefei; Herhaus, Lina; Zhang, Jianming; Pauls, Eduardo; Ham, Youngjin; Choi, Hwan Geun; Xie, Ting; Deng, Xianming; Buhrlage, Sara J.; Sim, Taebo; Cohen, Philip; Sapkota, Gopal; Westover, Kenneth D.; Gray, Nathanael S.
2018-09-27	First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia	Cho, Hanna; Shin, Injae; Ju, Eunhye; Choi, Seunghye; Hur, Wooyoung; Kim, Haelee; Hong, Eunmi; Kim, Nam Doo; Choi, Hwan Geun; Gray, Nathanael S.; Sim, Taebo
2019-10-24	Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis	Han, Youngsun; Sengupta, Sandip; Lee, Byung Joo; Cho, Hanna; Kim, Jiknyeo; Choi, Hwan Geun; Dash, Uttam; Kim, Jin Hyoung; Kim, Nam Doo; Kim, Jeong Hun; Sim, Taebo
2017-02-23	Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277	Cho, Hanna; Sengupta, Sandip; Jeon, Sean S. H.; Hur, Wooyoung; Choi, Hwan Geun; Seo, Hong-Seog; Lee, Byung Joo; Kim, Jeong Hun; Chung, Minhwan; Jeon, Noo Li; Kim, Nam Doo; Sim, Taebo
2021-08	Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3	Cho, Hanna; Shin, Injae; Yoon, Hojong; Jeon, Eunhye; Lee, Jiwon; Kim, Younghoon; Ryu, Seong Shick; Song, Chiman; Kwon, Nam Hoon; Moon, Youngji; Kim, Sunghoon; Kim, Nam Doo; Choi, Hwan Geun; Sim, Tae Bo
2012-02-18	Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers	Ham, Young Jin; Yu, Hana; Kim, Nam Doo; Hah, Jung-Mi; Selim, Khalid B.; Choi, Hwan Geun; Sim, Taebo
2013-02-06	Stereoselective synthesis of (-)-8-epi-swainsonine starting with a chiral aziridine	Lee, Baeck Kyoung; Choi, Hwan Geun; Roh, Eun Joo; Lee, Won Koo; Sim, Taebo
2013-12	Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones	Deng, Xianming; Elkins, Jonathan M.; Zhang, Jinwei; Yang, Qingkai; Erazo, Tatiana; Gomez, Nestor; Choi, Hwan Geun; Wang, Jinhua; Dzamko, Nicolas; Lee, Jiing-Dwan; Sim, Taebo; Kim, NamDoo; Alessi, Dario R.; Lizcano, Jose M.; Knapp, Stefan; Gray, Nathanael S.
2010-09-01	The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride	Ham, Young Jin; Lee, Duck-Hyung; Choi, Hwan Geun; Hah, Jung-Mi; Sim, Taebo
2014-01-03	Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor	Lim, Sang Min; Westover, Kenneth D.; Ficarro, Scott B.; Harrison, Rane A.; Choi, Hwan Geun; Pacold, Michael E.; Carrasco, Martin; Hunter, John; Kim, Nam Doo; Xie, Ting; Sim, Taebo; Jaenne, Pasi A.; Meyerson, Matthew; Marto, Jarrod A.; Engen, John R.; Gray, Nathanael S.

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